Value Analysis of Sperm Spontaneous Acrosome Reaction in Male Fertility Evaluation

Objective: Using correlation analysis between the sperm spontaneous acrosome reaction rate (SARR) and routine semen parameters in male infertility patients, we explored the value of the sperm spontaneous acrosome reaction in the evaluation of sperm functions. Methods: The participants comprised of 219 male infertility patients who had visited the Center for Reproductive Medicine, Shandong University from October 2016 to March 2017. According to the sperm SARR, we classified the patients with infertility into the control group and the case group. According to the WHO human semen examination and processing laboratory manual, fifth edition, recommendations and standards. We obtained routine semen parameters including semen volume, sperm concentration, total motility, and progressive sperm rate, and we measured sperm motility rate and the proportion of sperm with normal morphology. Results: With regard to the total motility, progressive sperm rate, sperm survival rate and the proportion of sperm with normal morphology, there were statistically significant differences between the two groups (p<0.01), but the data concerning patients’ age, semen volume, or sperm concentration showed no significant difference (p>0.05). Conclusion: Sperm SARR in patients with infertility is closely related to routine semen parameters and plays a supplementary reference in male fertility evaluation.